It is not Tik Tok, her first song was probably when she was a small child, singing to her own will. If you are talking about her first released/ breakthrough song, it is probably Right Round (she was featured as the girls part, the main parts were from Flo Rida).
Kesha's first song was ' Tick Tock ' it was the first one on the radio that we heard her singing.
Tik tok